For Severe Deficiency and Medical Conditions : Hydroxocobalamin injections are preferred, especially if you need long-lasting effects or have absorption issues
Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone [PMID: 37375736] Laboratory literature summary: Innate Vascular Failure by Application of Neuroleptics, Amphetamine, and Domperidone Rapidly Induced Severe Occlusion/Occlusion-like
Patients with more severe or longstanding deficiency may take longer to notice the full benefit
Low levels of B12 are associated with issues such as anxiety, depression, and cognitive decline
While saline can be appropriate for isotonic delivery in some contexts, the preservative advantage makes it the only reasonable choice for any protocol that needs to draw from the same vial across more than a single day